The UWO dataset includes anatomical and fMRI data from 12 monkeys.
Creative Commons – Attribution-NonCommercial Share Alike (CC-BY-NC-SA)- Standard INDI data sharing policy. Prohibits use of the data for commercial purposes.
- Siemens Magnetom 7T
- Custom-made 24-channel phased array receive coil with an 8-channel transmit coil.
Gilbert KM, Gati JS, Barker K, Everling S, Menon RS (2016) Optimized parallel transmit and receive radiofrequency coil for ultrahigh-field MRI of monkeys. Neuroimage 125:153-161
- Sample size: 12
- Age distribution: 4-8 years
- Weight distribution: 6.1-11.8 kg
- Sex distribution: All male
Click here for the full sample description (.csv)
Scan Procedures and Parameters
Ethics approval: Experimental procedures on nonhuman primates were in accordance with the Canadian Council of Animal Care policy and a protocol approved by the Animal Use Subcommittee of the University of Western Ontario Council on Animal Care.
Animal care and housing: Pair-housed animals
Any applicable training: none
Anesthesia procedures: Animals were first sedated with 0.1-0.2 mg/kg acepromazine, followed by 7.5 mg/kg ketamine hydrochloride by intramuscular injection. Anesthetic induction was accomplished by the administration of 2.5mg/kg propofol via an intravenous catheter in the saphenous vein. Anesthesia was maintained with 1 to 2% isoflurane with oxygen (1.5-2 L/min) through endotracheal intubation and it was reduced to 1% during fMRI acquisition.
Time between anesthesia and scanning: Monkeys were placed in the scanner as soon as isoflurane anesthesia was initiated and stable.
Head fixation: Animal with an implant (see full sample description) were head fixed using a head post.
Position in scanner and procedure used: Sphinx position
Contrast agent: none
Physiological monitoring: Heart rate and SpO2 were monitored throughout via a pulse oximeter and end-tidal CO2 and respiration rate were monitored via a capnometer.
Additional procedures: Temperature was recorded before and after the scans and was maintained within the normal range using heating discs, covers, and thermal insulation. Animals received subcutaneous fluids (10 ml/kg/hr) before and after the scan.
- Voxel resolution: 1.0 x 1.0 x 1.0 mm
- TE: 18ms
- TR: 1000ms
- MPRAGE Sequence
- Voxel resolution: 0.5 x 0.5 x 0.5 mm
- TE: 3.88ms
- TR: 65000ms
- TI: 800ms
- TI: 2700ms
- Flip angle: 4°
Click here for scan parameters from the scanner console (pdf).
- Ghahremani M, Hutchison RM, Menon RS, Everling S (2017) Frontoparietal functional connectivity in the common marmoset. Cerebral Cortex 27 (8): 3890-3905
- Stefan Everling1
- Ravi Menon2
1Department of Physiology and Pharmacology, University of Western Ontario, London, Ontario, Canada
2Departments of Medical Biophysics, Medical Imaging, Neuroscience, and Psychiatry, University of Western Ontario, London, Ontario, Canada
We would like to thank N. Hague and A. Kirley for expert veterinary care and T. Szekeres and J. Gati for MR expertise.
- Canadian Institutes of Health Research
- Natural Science and Engineering Research Council
- Brain Canada
Click here to download the data. Users will first be prompted to log on to NITRC and will need to register with the 1000 Functional Connectomes Project website on NITRC to gain access to the PRIME-DE datasets.